Will delayed release metformin provide better management of diabetes type 2?

Will delayed release metformin provide better management of diabetes type 2?

Metformin for prevention of type 2 diabetes.

OBJECTIVE To evaluate evidence from the medical literature that metformin is effective in preventing type 2 diabetes. DATA SOURCES Primary literature was accessed via a MEDLINE search (1966-December 2003) using the terms metformin, type 2 diabetes, and prevention. DATA SYNTHESIS Two studies evaluated metformin's potential to prevent type 2 diabetes, finding that metformin maintained or redu...

Metformin and Exercise in Type 2 Diabetes

OBJECTIVE To determine the effect of metformin on the acute metabolic response to submaximal exercise, the effect of exercise on plasma metformin concentrations, and the interaction between metformin and exercise on the subsequent response to a standardized meal. RESEARCH DESIGN AND METHODS Ten participants with type 2 diabetes were recruited for this randomized crossover study. Metformin or ...

Metformin and Cancer in Type 2 Diabetes

Corresponding author: Hyeong Kyu Park Department of Internal Medicine, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, 59 Daesagwan-ro, Yongsan-gu, Seoul 140-743, Korea E-mail: [email protected] Many epidemiologic studies have demonstrated a link between type 2 diabetes and an increased risk of certain cancers, and cancer-related mortality [1,2]. A number of me...

Pioglitazone-Metformin Extended-Release Fixed-Dose Combination for the Treatment of Type 2 Diabetes

Background: Combination oral glucose-lowering drug therapy is often required to maintain glycemic control in patients with type 2 diabetes. Single-tablet fixed-dose combinations of oral glucose-lowering agents provide one means to increase adherence, which may improve metabolic and clinical outcomes. A new fixed-dose combination of pioglitazone and extended-release metformin has recently been a...